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eofinternationalclinicaltrialsisunderwayforarecombinantCOVID-19vaccinedevelopedbyChineseresearchers,CCTVreportedonWednesday. DevelopedbyateamledbyMajorGeneralChenWei,academicianatthePeople'sLiberationArmy(PLA)AcademyofMilitaryMedicalSciences,thevaccinewasoneofthefirsttoenterthefirstandthenthesecondphaseofclinicaltrialsdomesticallyandinternationally. OnJanuary26,ChenledateamtoWuhanincentralChina'sHubeiProvincetofighttheepidemiconthefrontline.AfterarrivinginWuhan,Chen'steamstartedbuildingaportabletestinglab,whichstartedoperationonJanuary30.Thelabsoonachievedthete1

stingcapabilityof1,000peopleperday. OnMarch16,theCOVID-19vaccinedevelopedbyChenandherteambecamethefirsttobeapprovedbyChinaforclinicaltrials. ThevaccineenteredthesecondphaseofclinicaltrialsonApril12.ItisthefirstCOVID-19vaccineinth9

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. "Alargeamount AcoronavirusvaccinecandidatedevelopedbyaunitoV

nedcompanywillalsosupplythecandidatetoPakistanaspartofatrialagreement,theWallStreetJournalreported. Theshotdidnotcauseanyserioussideeffects,accordingtoapaperpublishedonThursdayintheJournaloftheAmericanMedicalAssociation(JA3

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herChina-baseddiseasecontrolauthoritiesandresearchinstitutes. Theresultswerebasedondatafrom320healthyadultsinPhase1and2trials. Thecandidatetriggeredrobustantibodyresponsesininoculatedpeople,butitremainedunknownifthatwassuff

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,whichhaskilledmorethan750,000peopleglobally,haspromptedaracetodevelopavaccine.MoretW

han150candidatevaccinesarebeingdevelopedandtestedaroundtheworld. Russiabecamethefirstcountrytograntregulatoryapprovaltoavaccineafterlessthantwomonthsofhumantesting,andashotdev7

elopedbyChinesefirmCanSinoBilogicshasbeenclearedforuseinthemilitary. Chinaisleadingthedevelopmentofatleasteightvaccinecandidatesindifferentstagesofclinicaltrials. ofresearchneedstobedonebeforewestartclinicaltrialssoastomin6

imizerisks,"ChentoldCCTVinaninterviewonWednesday. Chenandherteamtookastep-wiseapproachinclinicaltrials,startingwiththeminimumdoseandnF

umberofvolunteers. "Whatyouseeisthatwehaveonevaccineundergoingclinicaltrials,butbehindthatwehaveabout30candidates,"shesaid. Chen,whohasmademajorachievementsinCOVID-19-relatedbasicresearchanddeveloI

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